Neurology: Women’s Estrogen To The Nerves
October 9th 2009 -
Women get sick in certain periods of life increased with neurological disturbances. Debt could be the influence of hormones on the nerve messenger material Dopamine.
Neurological illnesses such as Parkinson, ADHS or the Tourette syndrome decrease/go back to a disturbance in dopamine transport. On the responsible person obviously also estrogen influence take DAT protein. That would explain, why there is a sex-specific difference for the time of the occurrence or the degradation of the illnesses.
Women for neurological disturbances are particularly susceptible during puberty, a pregnancy or in the change years. In these periods of life it comes to substantial hormone fluctuations. Therefore Rebecca Alyea and Cheryl Watson of the university of Texas in Galveston examined the influence of the estrogen on the nerve courses, particularly for the signal paths of the nerve messenger material Dopamine. They used for it nerve cells of rats, which had receptors for three natural estrogen.
Estrogen impairs dopamine transport
The female scientists determined an intensive interrelation of the estrogen receptors with the DAT protein, which removes normally surplus Dopamine from the connections between the nerve cells. estrogen obstructed the dopamine evacuation, which is important for healthy nerves.
“The connection of estrogen and DAT activity can supply new realizations in addition, like much sex and life phase on DAT dependent nerve illnesses affects themselves”, summarizes Cheryl Watson the study result. “That could lead also to new therapies against disturbances, which are connected with strong hormone fluctuations, approximately against the childbed depression.”
Tags: Estrogen, Neurology, parkinson, the nerves
