Hormone Therapy: Sensitive Breasts as Warning Signs of Cancer
October 25th 2009 -
Women who complain of the start of hormone replacement therapy on painful breasts appear to have an increased risk for breast cancer. As scientists of the University of California (Los Angeles) discovered, infected women who took estrogen and progestin regularly, 48 percent more often in an invasive breast cancer if her breasts were the hormones become sensitive to pain. “It is too early to advise women to discontinue hormone therapy,” says study leader Dr. Carolyn J. Crandall, a professor at the School of Medicine. In women whose breasts have become more sensitive by the hormones, but they should at least, the benefits and risks of therapy to be carefully weighed up.
The study is based on data from the Women’s Health Initiative (WHI), an American long-term study of the leading causes of death and health problems of women in menopause. One of the WHI study started in the 90s, with nearly 17,000 women and examined the effects of hormone replacement therapy with estrogen plus progesterone. She was terminated prematurely in 2002 after it was discovered that the women under the influence of hormones significantly more likely to have developed an invasive breast tumor.
In analyzing the data collected Crandall and her colleagues discovered a risk marker for a later breast cancer: the sensitivity of the breasts. Of the more than 8500 women who regularly swallow the hormone cocktail, got 36 percent of breast tenderness – compared to only 12 percent in the placebo group. And these women were diagnosed in an observation period of almost six years, significantly more often from cancer than those in which the treatment of chest pain sensitivity had not changed.
Why is the breast tissue of women reacted differently to the hormones is unclear. “There must be some differences in breast tissue, which believes make it more or less sensitive to hormones, Mary B. Daly of Fox Chase Cancer Center in Philadelphia. And Crandall suggested: “The sensitivity of the breasts a sign could be that the cells divide very quickly” – which is a risk factor for cancer.
Tags: hormone therapy, sensitive breast
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