Saliva Changes With The Years of Its Composition
November 20th 2009 -
In the course of a woman’s life is changing the composition of proteins in saliva in a characteristic way. This was discovered by American researchers saliva analysis of seven women aged 20 to 30 years and between 55 and 65 years.
Scientists given several hundred different proteins that are involved in the organism in such diverse tasks as the immune system, the regulation of digestive processes, or the transmission of signals. Over 260 of these substances were either solely or exclusively on the younger among women beyond the menopause. Let the normal composition for each age group known could help in future analysis of saliva in the diagnosis of diseases and developmental disorders.
The scientists took their study among women and examined the saliva samples contained proteins with highly sensitive analytical techniques. The researchers were able to pin down a total of 532 different proteins carrying out the immune response to the signal transfer almost all kinds of tasks in an organism. Striking were the extreme differences in the composition of these proteins in the two age groups: While 266 proteins occurred in both the young and the older women who were also only 266 different proteins in either one or the other group detected.
The biggest differences the researchers found in proteins involved in immune responses: Here are the older women were compared with the younger significantly increased presence of proteins, as the scientists discovered. This shift was reflected in the development of the female body reflected on the change of years, said the researchers. The analysis of saliva, however, could also be an important tool in the early diagnosis of diseases, including diseases such as lupus, say, with dry mouth and dry eyes associated Sjogren’s syndrome and many other autoimmune diseases, the scientists.
Previously doctors were mainly the blood and its components for the analysis of diseases. The results showed that in old age can be obtained from a study of saliva important information on health status and the development of the organism, explain the researchers. Saliva samples were mainly the advantage that they can be removed easily and without pain for the patient.
Tags: protein, saliva, sjogren's syndrome
